Institute Research Student Seminars
Speakers: Sadaf Atarod, PhD student (Haematology)
and Salah Abohelaika, PhD student (Pharmacology & Toxicology)
Date and time: Wednesday 12 February 2014 at 1.00pm
Sadaf Atarod will present:
“MicroRNAs in Graft-Versus-Host Disease”.
Identifying and investigating the role of microRNAs in graft-versus-host disease
at the molecular level.
Key words: microRNA, graft-versus-host disease and allogeneic transplantation
Salah Abohelaika will speak on:
“The impact of dietary vitamin K on the pharmacological activity of FXa inhibitor rivaroxaban
The impact of dietary vitamin K on anticoagulation response to warfarin is well established. However, the impact of diet on the pharmacological activity of newer oral anticoagulants is unknown. The impact of dietary vitamin K was evaluated in a group of healthy volunteers with adequate diet and a group of elderly medically stable patients with perceived poor diet. Clotting times and clotting protein activity was measured for each individual over a range of rivaroxaban concentrations ex-vivo. Dietary vitamin K status was established through the use of a validated dietary questionnaire.
Keywords: Novel oral anticoagulants, Rivaroxaban, Vitamin K, Diet, Anticoagulation
Chair: Laura Corbett, PhD student (Liver)