Thursday 24 July 2014

Pharmacogenomics and Cardiovascular Disease

A quick reminder that our next cross Institute Cardiovascular research group seminar is THIS Friday  25th July) at 1pm at Medical school! Dental lecture theatre D.

 

Title:'Relevance of Pharmacogenomics to Treatment of Cardiovascular Disease'

 

Presented by Professor Ann Daly, Institute of Cellular Medicine

 

 

 

 

 

Wednesday 23 July 2014

Joint Replacement, Osteoarthritis and Tissue Engineering Triple Bill

This is just to remind you that the MRG Lab Meeting will take place on Friday 25th July 2014 at 9.00am in the Baddiley Clark Lecture Theatre.
 
Chair
 
Katie Crossland - Post Doc (PI – Desa Lilic)
 
Speakers
 
Ramsay Refaie - MD Student (PI - Kenny Rankin) - Title of Talk "Diagnostic biomarkers in infected joint replacement"
 
Dimitra Tsompani - PhD Student (PIs - David Young and Drew Rowan) - Title of Talk "The role of Histone Deacetylase 3 in chondrogenesis and osteoarthritis''
 
Fabio D'Agostino - PhD Student (PI - John Loughlin) - Title of Talk to be confirmed
 
Thank you
 
Carol
 
 

Kasia Pirog describes the work of the SYBIL systems biology project at Newcastle University

Kenny Dalgarno describes the work of the Tissue Engineering Centre

Thursday 17 July 2014

T and B cell responses to carbamylated antigens

Jeroen Stoop will visit us next Friday 25 July.

 

Jeroen will give a talk on 'T and B cell responses to carbamylated antigens' at 4 pm in the Mitochondrial meeting room, 4th floor Cookson building. If you're curious what Jeroen has been up to since he left the MRG, please attend the talk.

 

Thursday 10 July 2014

Molecular Biology of Musculoskeletal Ageing

Seminar by Dr James Edwards from University of Oxford

 

Tuesday 15 July, 12:30 in the Great Gable seminar room, CAV

Title: Musculoskeletal Ageing – Targeting longevity mechanisms to preserve skeletal health 

Abstract:

There is a universal link between the ageing process and the deterioration of the musculoskeletal system. The loss of bone mass and strength, elevated cartilage and tendon wear and failure, combined with significant muscle weakening and frailty are all features seen within the ageing population and represent significant healthcare challenges worldwide.

Our group is focused upon the identification and manipulation of ageing-related mechanisms to not only explore the potential for increasing lifespan but also to protect against age-related disorders of the musculoskeletal system by improving therapeutic options, surgical procedures and increasing our knowledge of the ageing process in disease pathogenesis

Recent work has focused upon the role of the sirtuin gene family in bone and cartilage biology, the effects of dietary regimes on the skeleton and how the cellular recycling process of autophagy may be dysregulated with age to impact cells of the musculoskeletal system. 

http://www.ndorms.ox.ac.uk/profiles.php?profile=jedwards

 

Wednesday 9 July 2014

Why take part in research?

“By participating in research we ensure that our children, and our children’s children will not have to live with arthritis.”

RA Patient, Arthritis Matters Meeting, Newcastle University 2014

Professor John Isaacs and "The Patient Who Changed My Life"

Tuesday 8 July 2014

Healthcare Decisions & Clinical Decision Making

Professor Catherine Pope, Professor of Medical Sociology, University of Southampton

 

Healthcare call handling - decision making inside and outside the machine

 

Abstract: Clinical decision support systems (CDSS) are computer software programmes designed to assist healthcare decision-making. We have undertaken two studies looking at a CDSS which has been successfully deployed in UK emergency and urgent care settings since 2008 (and which underpins the new NHS 111 service). In looking at the performance of call handling we have revisited ideas about the location of expertise -  inside the machine (expert algorithms) and outside it (in the skills of human call handlers). In doing this we have examined the acquisition of clinical knowledge by non-clinical staff and the role of the wider team in managing calls. Exploration of these themes, alongside re-reading Haraway (amongst others) has led us to consider human-machine configurations and cyborgs. In this paper I describe where this journey has taken us and attempt to develop ideas about 'cyborg practices' to understand how technologies are practically enacted and continuously performed in complex healthcare settings. The empirical analysis in this paper is based on approximately 850 hours of observation in healthcare call centres and related sites, semi-structured interviews with 64 individuals and six focus groups with 6-9 individuals supplemented with contextual material from two surveys of health service staff.

 

Biography: Catherine Pope (Professor of Medical Sociology) is an internationally recognised expert on qualitative research in health care, leading sociological research aimed at changing the way the health and medical profession thinks about and conducts research.  Her work applies theory and research tackling the ‘wicked problems’ surrounding how best to organize and deliver modern healthcare, with emphasis on everyday healthcare practice, and the impacts of policy and organisational change on these. Professor Pope’s most recent work combines sociology and ethnography to explore urgent and emergency care, decision-making, communication and technologies in use.

 

WEDNESDAY 9th JULY 2014 

TIME:    12.45 - 2.00

VENUE:   Baddiley Clark Seminar Room

 

Musculoskeletal Ageing CARU 15th July 12.30 Arthritis, Bone, Cartilage

Tuesday 15 July 2014, 12.30pm
Great Gable Seminar Room, CARU
Speaker: Dr James Edwards, Marie Curie Fellow, University of Oxford
Title: Musculoskeletal Ageing - Targeting longevity mechanisms to preserve skeletal health
Abstract:
There is a universal link between the ageing process and the deterioration of the musculoskeletal system. The loss of bone mass and strength, elevated cartilage and tendon wear and failure, combined with significant muscle weakening and frailty are all features seen within the ageing population and represent significant healthcare challenges worldwide.
Our group is focused upon the identification and manipulation of ageing-related mechanisms to not only explore the potential for increasing lifespan but also to protect against age-related disorders of the musculoskeletal system by improving therapeutic options, surgical procedures and increasing our knowledge of the ageing process in disease pathogenesis
Recent work has focused upon the role of the sirtuin gene family in bone and cartilage biology, the effects of dietary regimes on the skeleton and how the cellular recycling process of autophagy may be dysregulated with age to impact cells of the musculoskeletal system.

Friday 4 July 2014

ICM Summer Meeting 7 July 2pm Lecture Theatre C Dental School

                                       
    ICM Summer Meeting
       Monday  7 July 2014
         Lecture Theatre C, Dental School at 2pm

          Agenda

      Welcome
      Review of the year
      Expectations for next year
      Refreshments and networking

           All Invited

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