Institute Research Student Seminars
Speakers: Siti Mohamad & Eleana Pappa
Date and time: Wednesday 10th December 2014 at 12.30
Siti Mohamad will present:
"A novel defect in the IFN alpha signalling pathway"
(Sophie Hambleton: Primary Immunodeficiency Group)
IFN alpha signalling is responsible for protecting the body against viruses. We found a novel defect in the IFN alpha signalling pathway in a patient with a severe disseminated MMR vaccine.
Key words: Viral susceptibility, IFN alpha signalling, novel defect
Eleana Pappa will discuss:
"Transcriptional and Phenotypic Characterization of Hepatic Stellate Cells"
(Derek Mann: Fibrosis Group)
Correlation of liver stiffness with fibrosis progression has been observed in many liver diseases. Hepatic stellate cells (HSC) are the main scaring forming cells in liver fibrosis. Activation of HSC from quiescent to myofibroblasts is the initial step for fibrosis development. In this project we evaluate the importance of substrate stiffness as driving force for HSC activation.
Key words: Liver fibrosis, Hydrogels, HSC
Chair: Kile Green