Plasmacytoid Dendritic Cell Subsets in RA and SLE

 

 

 

 

Institute Research Student Seminars

Speaker:  Faye Cooles

 

Venue: Seminar room L2.5, 2^nd floor, William Leech Building, Medical School

Date and time:  Wednesday 14^th January 2015 at 12.30

 

Faye Cooles will present:

 

“Plasmacytoid Dendritic Cell Subsets in RA and SLE”

(John Isaacs, Catharien Hilkens and Amy Anderson: MRG)

 

Plasmacytoid dendritic cells (pDCs) are a relatively newly identified dendritic cell sub-type. They are the body's main producers of interferon-alpha and have been implicated in a number of autoimmune diseases, mainly systemic lupus erythematous (SLE). In this work we aim to dissect the implications of pDC subsets on interferon-alpha production and clinical phenotype in SLE and rheumatoid arthritis.

 

Key words: Interferon-alpha, Plasmacytoid Dendritic Cells, Autoimmunity

 

Chair: Jenny Grant