Tuesday 7 July 2015

ICM PI Seminar Today




PI Seminar Series


Speaker: Professor Ann Daly, Professor of Pharmacogenetics


Venue: Lecture Theatre C, Dental School


Time and Date: 7th July 2015 13.00-14.00


Professor Ann Daly will present:





Drug-induced liver injury (DILI) is a rare but serious problem with certain widely prescribed drugs and can result in liver failure. It is also a relatively common cause of drug attrition during development. Progress on identifying genetic risk factors for DILI due to a range of drugs using genome-wide association studies will be considered. The genetic associations we have seen, involving both HLA and non-HLA genes, provide new insights into the underlying mechanisms for idiosyncratic DILI and may assist in the development of improved strategies for its prediction and diagnosis.


Chair: Dr Quentin Anstee





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