Wednesday, 30 July 2014
Thursday, 24 July 2014
Pharmacogenomics and Cardiovascular Disease
A quick reminder that our next cross Institute Cardiovascular research group seminar is THIS Friday 25th July) at 1pm at Medical school! Dental lecture theatre D.
Title:'Relevance of Pharmacogenomics to Treatment of Cardiovascular Disease'
Presented by Professor Ann Daly, Institute of Cellular Medicine
Wednesday, 23 July 2014
Joint Replacement, Osteoarthritis and Tissue Engineering Triple Bill
Tuesday, 22 July 2014
Monday, 21 July 2014
Arthritis Research Posters from RACE
Thursday, 17 July 2014
T and B cell responses to carbamylated antigens
Jeroen Stoop will visit us next Friday 25 July.
Jeroen will give a talk on 'T and B cell responses to carbamylated antigens' at 4 pm in the Mitochondrial meeting room, 4th floor Cookson building. If you're curious what Jeroen has been up to since he left the MRG, please attend the talk.
Thursday, 10 July 2014
Molecular Biology of Musculoskeletal Ageing
Seminar by Dr James Edwards from University of Oxford
Tuesday 15 July, 12:30 in the Great Gable seminar room, CAV
Title: Musculoskeletal Ageing – Targeting longevity mechanisms to preserve skeletal health
Abstract:
There is a universal link between the ageing process and the deterioration of the musculoskeletal system. The loss of bone mass and strength, elevated cartilage and tendon wear and failure, combined with significant muscle weakening and frailty are all features seen within the ageing population and represent significant healthcare challenges worldwide.
Our group is focused upon the identification and manipulation of ageing-related mechanisms to not only explore the potential for increasing lifespan but also to protect against age-related disorders of the musculoskeletal system by improving therapeutic options, surgical procedures and increasing our knowledge of the ageing process in disease pathogenesis
Recent work has focused upon the role of the sirtuin gene family in bone and cartilage biology, the effects of dietary regimes on the skeleton and how the cellular recycling process of autophagy may be dysregulated with age to impact cells of the musculoskeletal system.
http://www.ndorms.ox.ac.uk/profiles.php?profile=jedwards
Wednesday, 9 July 2014
Why take part in research?
“By participating in research we ensure that our children, and our children’s children will not have to live with arthritis.”
RA Patient, Arthritis Matters Meeting, Newcastle University 2014
Tuesday, 8 July 2014
Healthcare Decisions & Clinical Decision Making
Professor Catherine Pope, Professor of Medical Sociology, University of Southampton
Healthcare call handling - decision making inside and outside the machine
Abstract: Clinical decision support systems (CDSS) are computer software programmes designed to assist healthcare decision-making. We have undertaken two studies looking at a CDSS which has been successfully deployed in UK emergency and urgent care settings since 2008 (and which underpins the new NHS 111 service). In looking at the performance of call handling we have revisited ideas about the location of expertise - inside the machine (expert algorithms) and outside it (in the skills of human call handlers). In doing this we have examined the acquisition of clinical knowledge by non-clinical staff and the role of the wider team in managing calls. Exploration of these themes, alongside re-reading Haraway (amongst others) has led us to consider human-machine configurations and cyborgs. In this paper I describe where this journey has taken us and attempt to develop ideas about 'cyborg practices' to understand how technologies are practically enacted and continuously performed in complex healthcare settings. The empirical analysis in this paper is based on approximately 850 hours of observation in healthcare call centres and related sites, semi-structured interviews with 64 individuals and six focus groups with 6-9 individuals supplemented with contextual material from two surveys of health service staff.
Biography: Catherine Pope (Professor of Medical Sociology) is an internationally recognised expert on qualitative research in health care, leading sociological research aimed at changing the way the health and medical profession thinks about and conducts research. Her work applies theory and research tackling the ‘wicked problems’ surrounding how best to organize and deliver modern healthcare, with emphasis on everyday healthcare practice, and the impacts of policy and organisational change on these. Professor Pope’s most recent work combines sociology and ethnography to explore urgent and emergency care, decision-making, communication and technologies in use.
WEDNESDAY 9th JULY 2014
TIME: 12.45 - 2.00
VENUE: Baddiley Clark Seminar Room
Musculoskeletal Ageing CARU 15th July 12.30 Arthritis, Bone, Cartilage
Great Gable Seminar Room, CARU
Speaker: Dr James Edwards, Marie Curie Fellow, University of Oxford
Title: Musculoskeletal Ageing - Targeting longevity mechanisms to preserve skeletal health
Abstract:
There is a universal link between the ageing process and the deterioration of the musculoskeletal system. The loss of bone mass and strength, elevated cartilage and tendon wear and failure, combined with significant muscle weakening and frailty are all features seen within the ageing population and represent significant healthcare challenges worldwide.
Our group is focused upon the identification and manipulation of ageing-related mechanisms to not only explore the potential for increasing lifespan but also to protect against age-related disorders of the musculoskeletal system by improving therapeutic options, surgical procedures and increasing our knowledge of the ageing process in disease pathogenesis
Recent work has focused upon the role of the sirtuin gene family in bone and cartilage biology, the effects of dietary regimes on the skeleton and how the cellular recycling process of autophagy may be dysregulated with age to impact cells of the musculoskeletal system.