National Arthritis Week 2014, 12 to 19 October

This year, Arthritis Research UK's National Arthritis Week runs from 12 to 19 October 2014. I'd like to invite you to join us again and raise money for Arthritis Research UK. Find out about the events already planned nationwide, or request your fundraising guide online. The guide is packed with ideas to help you decide what you want to do, as well as tips to help you plan your fundraising activity.   How your fundraising helps The money you raise will help support your vital research. This will, in turn, help transform the lives of the millions of people affected by arthritis and also raise awareness of the impact of this disease, the biggest cause of pain and disability in the UK. Last year you helped raise £50,000 as well as raising awareness and supporting events nationwide.     What's National Arthritis Week 2014 about? We know that that the pain of arthritis is often invisible but we want everyone to know how agonising it can be to people of all ages. So this year we're highlighting the impact that long term pain has on the 10 million people living with arthritis in the UK. The aim is to reassure and inform people with arthritis that Arthritis Research UK understands what it's like to live with long term pain, and that we're here to support them as well as fighting to find a cure. Your support, through your research, spreading the word, and fundraising will bring us one step closer to this goal.     World Arthritis Day, Sunday 12 October National Arthritis Week 2014 starts on World Arthritis Day on Sunday 12 October. Supported and managed by EULAR, the European League Against Rheumatism, this global event is a fantastic opportunity to raise awareness of the impact and prevalence of arthritis in the UK, as well as available treatments and self-help management options.   Thank you for supporting National Arthritis Week and for the work you do for us all year round. With very best wishes, Pete Morley, Research Administration Officer. P.S. Need help or advice for your fundraising ideas? Email research@arthritisresearchuk.org and we'll put you in touch with your local representative who can help.

Professor John Isaacs and Great North Run 2014

 

Dear friends and colleagues

 

I’m afraid it’s that time of year again.  I have decided to run the 13.1 miles, Newcastle to South Shields, Great North Run one more time.  This will be my tenth successive year, which is my justification for putting up with the aches and pains for another year.  Also, last year you were incredibly generous and helped me to raise over £4000 for Arthritis Research UK, placing me in the top 1% of JustGiving fundraisers for the year.  And the main justification, of course, is indeed the fabulous charity that ultimately benefits from your generosity. 

 

There are only four weeks to go until the big day and I find myself, once more, in the final weeks of training.  And, once more, during every training run I hear the words in my head, ‘never again’.  But I have practically hit my £20,000 target over ten years of participation, and £25,000 is now looking tempting.  To help me reach this target, this year I will donate an additional 10p for every £1 that you pledge.  So please dig deep, as you always do, and make me wince with your generosity!

 

You can donate at: http://www.justgiving.com/jdi2014

 

Many thanks for helping research into arthritis and related conditions.

 

Best wishes, John

 

John D Isaacs

Director of the Institute of Cellular Medicine and Professor of Clinical Rheumatology

Newcastle University

 

Osteoarthritis Research

Osteoarthritis Research Day 10th September 2014

Grand Hotel - Tynemouth

12:00 - 18:00

12:00 LUNCH

13:00 Tim Hardingham, University of Manchester "The challenge of treating Osteoarthritis, a complex disease"

13:20 John Isaacs, Newcastle University "RA pathogenesis"

13:40 Dylan Edwards, University of East Anglia "Metalloproteinases as therapeutic targets – where to next?"

14:00 Fraser Birrell, Newcastle University, "OA"

14:20 Amy Naylor, University of Birmingham "The mesenchymal stromal cell marker CD248 in bone destruction and repair"

14:40 Ian Clark, University of East Anglia "'You are what you eat: can diet impact upon osteoarthritis?'"

15:00 Tea Break

15:30 Graham Riley, University of East Anglia "25 years studying tendon, and what do I know?"

15:50 David Young, Newcastle University "Epigenetics of chondrogenesis"

16:10 Tonia Vincent, University of Oxford "'shifting paradigms in OA pathogenesis'

16:30 John Loughlin, Newcastle University, "Functional genomics of OA"

16:50 Mary Goldring, Hospital for Special Surgery, NY "OA & cartilage"

17:10 Drew Rowan, Newcastle University "Proteinases, proteolysis and cartilage"

And Tim Cawston's Valedictory Address?

Latest News: STAT2 and TH17

Harriet A. Purvis, Amy E Anderson, David A. Young, John D. Isaacs and Catharien M. U. Hilkens.  

A negative Feedback Loop Mediated by STAT2 Limits Human TH17 Responses.    

The Journal of Immunology doi: 10.4049 - 1302467