Monday 30 January 2017

VIVA seminar Emma Rogers - Monday 6th February 2017, 11:00am

Emma Rogers (PGR); John Loughlin; Louise N. Reynard; Kenneth Rankin

Subject: VIVA seminar Emma Rogers - Monday 6th February 2017, 11:00am - Seminar Room L2.9 (2nd floor Medical School)



VIVA Seminar

Speaker: Emma Rogers
Supervisors: Prof J. Loughlin, Dr L. Reynard, Mr K. Rankin


'Molecular genetic and epigenetic analysis of osteoarthritis: A functional investigation of a single nucleotide polymorphism associated with female hip osteoarthritis'

- Osteoarthritis, genetics, gene expression -


The genetic architecture of osteoarthritis (OA) is highly complex, with heterogeneous pathological pathways converging on a common end phenotype. The aim of this project was to characterise a female hip OA association signal, marked by the single nucleotide polymorphism (SNP) rs4836732, using functional molecular genetic techniques.  Results suggest increased disease risk may be mediated during synovial joint development and have identified PAPPA, encoding a metalloproteinase, as a candidate target gene.



Monday 6th February 2017 – 11am
Seminar Room L 2.9
(second floor Medical School)












Wednesday 11 January 2017

Coming Soon - ARUK Rare Musculoskeletal Diseases - 3rd February 2017

Including our very own John Isaacs and Bridget Griffiths
Arthritis Research UK Clinical Study Groups:

Adult Inflammatory Arthritis

Metabolic bone disease and musculoskeletal trauma

Autoimmune rheumatic disorders

Medicines for Children


Improving clinical research in rare musculoskeletal diseases: challenges and opportunities?


Friday 3rd February 2017, 10am – 5.00pm


Venue: The Light, Friends House, Euston Road, London