David Westhead – University of Leeds—Friday 6 June @ 1.15 pm, Research Beehive room 2.21
"High-throughput data, bioinformatics and its application to normal and aberrant genetic regulation in blood cells"
High-throughput sequencing has revolutionised our ability to generate data relevant to genetic regulation. I will discuss recent work we have been doing to integrate expression data (RNA-seq) with ChIP-seq data for transcription factor binding and chromatin marking in order to understand the genetic regulation of blood cell (myeloid) development. I will also discuss our work on aberrant regulation in leukaemia and how we are starting to translate this work into the clinic.
Faculty contact: Diego Miranda-Saavedra (email@example.com), ext. 8590