Wednesday 25 March 2015

Featuring Nishanthi Thalayasingam and Peripheral Blood B Cells in Early Arthritis





ICM Research Seminar

Speakers:  Luke Richardson, PhD student (Laura Yates)


Nishanthi Thalayasingam, PhD Student (Arthur Pratt)


Venue: Seminar room L2.5, Second floor, Leech Building, Medical School

Date and time:  25th March 2015, 12:30


Luke Richardson will discuss:


"Spontaneous abortion risk in women using antidepressants during pregnancy"


Published estimates have suggested that approximately 10% of women will experience symptoms of depression during pregnancy, and the severity of these symptoms may on occasion justify gestational antidepressant use. Using routinely collected UK surveillance data and robust statistical analysis techniques, this study will analyse the spontaneous abortion rate (fetal loss prior to 24 weeks gestation) experienced following maternal antidepressant use during pregnancy



Nishanthi Thalayasingam will speak on:


"A microarray analysis of peripheral blood B cells from early arthritis patients"


In Rheumatoid Arthritis (RA) chronic inflammation leads to irreversible joint damage and so it is vital treatment is commenced promptly to prevent this. There is increasing interest in the role of B cells in the pathogenesis of RA following the effectiveness of selective B cell depletion. The purpose of this project is to identify potential diagnostic biomarkers for RA by comparing the gene expression profiles of B cells from newly diagnosed RA patients to that of patients diagnosed with other types of arthritis.



Chair:  Marco Silipo




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