PI Seminar Series
Speaker: Professor Ann Daly, Professor of Pharmacogenetics
Venue: Lecture Theatre C, Dental School
Time and Date: 7th July 2015 13.00-14.00
Professor Ann Daly will present:
'GENETIC RISK FACTORS FOR DRUG-INDUCED LIVER INJURY'
Drug-induced liver injury (DILI) is a rare but serious problem with certain widely prescribed drugs and can result in liver failure. It is also a relatively common cause of drug attrition during development. Progress on identifying genetic risk factors for DILI due to a range of drugs using genome-wide association studies will be considered. The genetic associations we have seen, involving both HLA and non-HLA genes, provide new insights into the underlying mechanisms for idiosyncratic DILI and may assist in the development of improved strategies for its prediction and diagnosis.
Chair: Dr Quentin Anstee