Dr Sinisa Savic
Consultant Clinical Immunologist and honorary Clinical Associate Professor,
St James's University Hospital, Leeds
Baddiley Clark Seminar Room
Monday 19th October 2015
13.00 – 14.00pm
Dr Sinisa Savic, MBBS, MRCP, MSc, MRCP (London), FRCPath, PhD will present:
Systemic autoinflammatory disorders:
pathophysiology and diagnosis in routine clinical practice
One of his main clinical and research interest is pathophysiology, diagnosis treatment of autoinflammatory conditions. His work in this area was initially focused on the pathogenesis of TNF Receptor periodic fever syndrome. More recently he has evaluated use of anakinra (anti-IL-1 biologic) in diagnosis of patients with undifferentiated (genetically undefined) autoinflammatory syndromes.
For the purposes of this meeting his presentation will include a brief overview of the principles which define the concept of autoinflammation. He will also present some of his work on the pathophysiology of TRAPS. He will talk about the crossover between of autoinflammation and autoimmunity and the role of these processes in the pathogenesis of more common conditions such as rheumatoid arthritis.
Chair: Dr Desa Lilic
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