Tuesday 25 February 2014

Tolerance and Inflammation



Institute Research Seminar


Guest speakers: Professor Andrew Mellor & Dr Lei Huang

[Leader, Cancer Immunology, Inflammation and Tolerance Programme, GRU Cancer Center
Bradley-Turner & GRA Eminent Scholar in Molecular Immunogenetics, Georgia, USA


Venue: Dental lecture theatre E, ground floor, Dental School

Date and time:  Wednesday 26 February 2014 at 4.00pm


Professor Mellor and Dr Huang will discuss:


"Pivotal pathways controlling the balance between tolerance and immunity

at sites of inflammation".


Tissue inflammation increases the risk of autoimmunity by breaking tolerance. Paradoxically, inflammation associated with tumours and some infections promotes tolerance. Dr Andrew Mellor and Lei Huang will describe their current research to evaluate host responses to DNA nanoparticles and murine leukemia virus as models to elucidate pivotal pathways that promote tolerance at sites of inflammation.


Key words:  Tolerance, inflammation   



Professor Mellor holds the Georgia Research Alliance Eminent Scholar Chair in Immunogenetics in the Department of Medicine at the Medical College of Georgia. He earned his BA and MA at the University of Cambridge, completing the latter in 1978. He was awarded his PhD by the University of London in 1979. He did post-doctoral work at the National Institute for Medical Research in London, followed by study with Dr. R.A. Flavell at the Biogen Research Corp. in Boston.




Professor Mellor and Dr Huang will be visiting ICM from 24 - 28 February 2014

Please contact Jenna Ho on ext 6227 or by email at jenna.ho@ncl.ac.uk if you would like

a meeting to be arranged.


*   Refreshments will be available in the Dental Bites café after the meeting   *


Chair:  Professor S Yeaman





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