GM-CSF, Dendritic cells, RA and Biofilm growth on fluoridated denture material

 

 

 

Institute Research Student Seminars

Speakers:  Gary Reynolds, PhD student (Musculoskeletal) and

Sufian Al-Sammarraie, PhD student (Oral & Dental Sciences)

 

Venue: Seminar room L2.5, 2^nd floor, Leech Building, Medical School

Date and time:  Wednesday 2 April 2013 at 1.00pm

 

Gary Reynolds will discuss:

 

"The role of T cell-derived GM-CSF in inflammatory dendritic cell development

in rheumatoid arthritis".

 

A monocyte-derived population of cells with characteristics of dendritic cells has been described in inflammatory states in mice. An equivalent population has been identified in humans but the factors governing their development are not clear. GM-CSF is implicated as it is employed in in-vitro models of monocyte-derived dendritic cell development. The role of synovial T cell-derived GM-CSF in this process is discussed.

 

Key words:   GM-CSF, Dendritic cells, Rheumatoid arthritis

 

____________________________________

Sufian Al-Sammarraie will speak on:

 

"Biofilm growth on fluoridated denture material”

 

In this study, we evaluated the efficacy of a new fluoride-releasing copolymer material for reducing single- and mixed-species biofilm formation on oral appliances. A model system has been developed for this study

 

 

Keywords:  Denture plaque, qPCR, Mixed biofilm

 

Chair:  Darren Johnson, PhD student (Dermatology)